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DEPARTMENT OF ANIMAL PHYSIOLOGY

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DEPARTMENT OF ANIMAL FYZIOLOGY

assoc. prof. Monika Kassayová, PhD.

Workplace: Institute of Biology and Ecology
Pavol Jozef Safarik University in Košice,
Faculty of Science
Address: , 040 01 Košice
Phone: +421 55 234-1214
Email: monika.kassayova@upjs.sk

Academic degrees
1996 - PhD.
2008 - Assoc. Prof.

Career
1985 -1990 – study at the Faculty of Science, P.J. Šafárik University in Košice
1990 -1992 – doctoral study, Department of Animal and Human Physiology Faculty of Science
1992 -1998 – research worker, Department of Animal and Human Physiology
1998 -2003 – motherhood (2 children)
2003 –2008 - teacher, Assistant Professor, Department of Animal Physiology, Institute of Biological and Ecological Sciences, Faculty of Science, P.J. Šafárik University in Košice
since 2008 - Associate Professor, Dept. Animal Physiology

Study
Lectures:
Cell Metabolism
Animal and Human Physiology
Endocrinology

Laboratory practices:
Cell Metabolism
Animal and Human Physiology
Diploma thesis supervisor

Research activities
Research is aimed at the study of:
- effects of whole-body and local gamma irradiation on pineal function and melatonin synthesis in rats,
- the role of psychoemotional stress in mammary tumorigenesis in rats
- chemoprevention of mammary carcinogenesis in female rats by non-steroidal anti-inflammatory drugs, melatonin, peroral antidiabetics

Membership
The Slovak Physiological Society – member
The Slovak Oncological Society – member

Projects
VEGA 1/1286/04
The role of psychoemotional stress in the origin of experimental mammary carcinogenesis in female rats – principal investigator

VEGA 1/2355/05
Prevention of mammary carcinogenesis in female rats by a selective inhibitors of cyclooxygenase-2 activity – principal investigator since 2007

VEGA 1/4321/07
Prevention of experimental mammary carcinogenesis in female rats by peroral antidiabetics

VEGA 1/4345/07
Effects of low doses of ionizing radiation on behaviour and neurogenesis in hippocampus in adult rats irradiated during various phases of embryonal development

Selected publications
Kubatka P, Kapinová A, Kello M, Kruzliak P, Kajo K, Výbohová D, Mahmood S, Murin R, Viera T, Mojžiš J, Zulli A, Péč A, Adamkov M, Kassayová M, Bojková B, Stollárová N, Dobrota D: Fruit peel polyphenols demonstrate substantial anti-tumour effects in the model of breast cancer. Eur J Nutr. 2015, [Epub ahead of print]

Kubatka P., Kapinová A., Kružliak P., Kello M., Výbohová D., Kajo K., Novák M., Chripková M., Adamkov M., Péč M., Mojžiš J., Bojková B., Kassayová M., Stollárová N., Dobrota D. Antineoplastic effects of Chlorella pyrenoidosa in the breast cancer model. Nutrition, In Press, Published Online: September 05, 2014.

Vašková J., Kassayová M., Vaško L.: Potential role of melatonin in DNA damage caused by nitrosourea-induced mammary carcinogenesis. Acta Histochem. xxx (2010), doi: 10.1016/j.acthis.2010.03.006

Bojková B., Garajová M., Kajo K., Péč M., Kubatka P., Kassayová M., Kisková T., Orendáš P., Ahlersová E., Ahlers I.: Pioglitazone in chemically induced mammary carcinogenesis in rats. Eur. J. Cancer Prev. 19, 379-384, 2010

Orendáš P., Kassayová M., Kajo K., Ahlers I., Kubatka P., Bojková B., Péč M., Ahlersová E.: Celecoxib and melatonin in prevention of female rat mammary carcinogenesis. Neoplasma 56, 252-258, 2009

Bojková B., Orendáš P., Garajová M., Kassayová M., Kútna V., Ahlersová E., Ahlers I.: Metformin in chemically-induced mammary carcinogenesis in rats. Neoplasma 56, 267-272, 2009

Bojková B., Orendáš P., Friedmanová L., Kassayová M., Ďatelinka I., Ahlersová E., Ahlers I.: Prolonged Melatonin Administration in 6-Month-Old Sprague-Dawley Rats: Metabolic Alterations, Acta Physiologica Hungarica 95, 65-76, 2008

Orendáš P., Ahlers I., Kubatka P., Ahlersová E., Bojková B., Kassayová M., Friedmanová L., Kisková J., Ďatelinka I., Starostová M.: Etoricoxib in the prevention of rat mammary carcinogenesis. Acta Veterinaria Brno 76, 613-618, 2007

Kassayová M., Friedmanová L., Orendáš P., Kubatka P., Bojková B., Bobrov N., Ahlersová E., Ahlers I.: Effect of prolonged psychoemotional stress and melatonin on experimental mammary carcinogenesis in female rats. Neoplasma 54(3), 251-255, 2007

Kassayová M., Adámeková E., Bojková B., Kubatka P., Ahlers I., Ahlersová E.: Effect of a short-term and long-term melatonin administration on mammary carcinogenesis in female Sprague-Dawley rats influenced by repeated psychoemotional stress. Acta Vet. Brno 76, 371-377, 2007

Kassayová M., Friedmanová L., Orendáš P., Bojková B., Bobrov N., Ahlersová E., Ahlers I.: Influence of immobilization stress on mammary tumour development. Acta Physiologica 191(Suppl. 658), p. 44, 2007

Kassayová M., Marková M., Bojková B., Adámeková E., Kubatka P., Ahlersová E., Ahlers I.: The influence of long-term melatonin administration on basic physiological and metabolic variables of young Wistar:Han rats. Biologia, Bratislava 61(3): 313-320, 2006

Kassayová M., Ahlersová E., Ahlers I.: The effect of single whole-body irradiation of pineal functions. In: Fundamentals for the assessment of risk from environmental radiation. C. Baumstark-Khan et al. (Eds.), Kluwer Academic Publishers, Dordrecht 1999, 401-405

Kassayová M., Ahlersová E., Ahlers I.: Two-phase response of rat pineal melatonin to lethal whole-body irradiation with gamma rays. Physiol. Res. 48, 227-230, 1999

Ahlersová E., Kassayová M., Ahlers I.: Serum melatonin, corticosterone and thyroid hormones in irradiated rats: Effect of exposure during various times of day and of light regimen. J. Physiol. Pharmacol. 48, 435-442, 1997

Ahlers I., Solár P., Ahlersová E., Kassayová M., Šmajda B.: The influence of melatonin on metabolic changes in female rats induced by continuous irradiation and/or administration of 7,12-dimethylbenz/a/anthracene. Neoplasma 44, 253-257, 1997

Kassayová M., Ahlersová E., Ahlers I., Pástorová B.: Exogenous melatonin influenced the pineal function in rats continuously irradiated with two different daily doses. In: Radiation biology and its application in space research. S. Kozubek, G. Horneck (Eds.), Brno 1995, 151-155

Kassayová M., Ahlersová E., Ahlers I., Pástorová B.: The early response of pineal N-acetyltransferase activity, melatonin and catecholamine levels in rats irradiated with gamma rays. Physiol. Res. 44, 315-320, 1995

Kassayová M., Ahlersová E., Ahlers I.: Pineal function in lethally irradiated rats. In: Radiation biology and its application in space research. S. Kozubek, G. Horneck (Eds.), Brno 1993, 98-100

Kassayová M., Ahlersová E., Ahlers I., Milárová R.: The changes in pineal N-acetyltransferase activity, pineal and serum melatonin concentration in rats after irradiation of the head. Physiol. Res. 42, 419-422, 1993

Kassayová M., Ahlersová E., Ahlers I.: Changes of pineal N-acetyltransferase activity in gamma irradiated rats. Physiol. Res. 42, 167-169, 1993